Wow, this one is pretty tough!
I did it on master just now with Fahz (me), Keegan and Kait - all of us were randomers and no mics. It took us several attempts. We took the Fabricator path in part 1 and the venom fans in part 2.
The venom creeps up on you pretty quick in places and in the section just before the helipad, there’s alot of enemies to fight. Just when you think you have cleared them all out, a few more show up including a surprise ambush from behind of two Sentinels. You’ll want to complete the initial fight (straight after the saferoom) quickly so you can stay ahead of the venom - there’s a fair amount to fight, so you’ll need breathing space!
In all, I think there must have been at least about 6 Sentinels plus 2 Guardians. It will vary depending on which path you take.
It gets easier as you become more familiar with the Hive. It’s especially important for Fahz as there are certain areas which benefit massively from your X-Ray ultimate, so knowing when to use it and when to save it can mean a big difference. Critical Parade is excellent and you can chain lots of kills using this. It’s harder with an EMBAR due to shorter zoom than the Longshot, and the active reload bar feels quite different, but if you get used to this, you can clear out lots of enemies.
I’ll save the score run for another day. I’m exhausted!